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Clamping Down on Transposon Targeting
Mick Chandler
1Laboratoire de Microbiologie et Génétique Moléculaire UMR 5100, CNRS, 31062 Toulouse CEDEX, France
Cell, Volume 138, Issue 4, 21 August 2009, Pages 685-695,
Adam R. Parks, Zaoping Li, Qiaojuan Shi, Roisin M. Owens, Moonsoo M. Jin, Joseph E. Peters
The sliding β clamp subunit of the DNA replication machinery in the bacterium Escherichia coli coordinates multiple functions in the cell beyond genome duplication. In this issue, Parks et al. (2009) find that the β clamp interacts with the transposition protein TnsE to target the Tn7 transposon to discontinuously replicating DNA at the replication fork.
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